Prompt Identify your selected case, describing how the normal physiology is changed by the disease state. In addition, define pathophysiology, the clinical manifestations (that is, signs and symptoms), and how each of these can be explained by alteration in physiology. Discuss the extent to which the clinical manifestations in the selected case affect multiple body systems. Include a historical analysis that describes the pathophysiology for the selected disease or illness. Propose historical explanations for variations in findings (when applicable) and include evidence-based resources to frame your discussion of adaptation and stressors for system analysis. Specifically for Milestone One, the following critical elements must be addressed: Introduce your selected case Identify the individual you selected and the illness and provide a brief explanation of why you selected this case. Describe how normal physiology is changed by the disease state for your selected case. Define the pathophysiology and general clinical manifestations associated with your selected case and how they may be explained by altered physiology. Be sure to support your claims with scholarly evidence. Assess the extent to which clinical manifestations of your selected case affect multiple body systems, using scholarly evidence to support your claims. History of selected case Describe historical variations (that is, examples of individuals with the selected disease or illness) of your selected case, using evidence from literature. Identify physiological stressors that may affect the course of the disease or illness and explain their impact. Identify adaptive physiological mechanisms that may affect the course of the disease for your selected case. Assess the historical impact of patient care technologies on patient outcomes for your selected case. Be sure to justify your claims with scholarly evidence. What to Submit Your paper must be submitted as a 4-6 page Microsoft Word document properly APA formatted with double spacing, 12-point Times New Roman font, one-inch margins, and any sources cited in APA format.
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